Effects of acetazolamide on linear growth in children with pseudotumor cerebri syndrome

نویسندگان

چکیده

Background/introduction While oral acetazolamide is a cornerstone of management adult and pediatric PTCS, previous studies have suggested that used in children with other conditions may influence growth. Aims methods Retrospective chart review involving single tertiary medical center. Thirty-four definite or probable PTCS were identified. Analysis was restricted to individuals from whom anthropometric data available before during treatment (n=22). Results Half (n=11/22) showed decline BMI Z-scores. Sixty-three percent (n=14/22) decrease height Z-scores acetazolamide; 6 these 14 who had complete data, 3 at least partial recovery after discontinuation acetazolamide. Conclusion Acetazolamide be associated growth suppression some treated for PTCS. In cases, the appears reverse once stopped.

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Brain Imaging in Pediatric Pseudotumor Cerebri Syndrome

Pseudotumor cerebri syndrome (PTCS) is an umbrella term used for the constellation of symptoms caused by increased intracranial pressure (ICP) without hydrocephalus, spaceoccupying lesion, or anomalies of brain parenchyma and with a normal cerebrospinal fluid (CSF) composition.1 PTCS has a reported incidence of 0.9 per 100,000 in the general population, but it rises to 19 per 100,000 in obese w...

متن کامل

[Pseudotumor cerebri in children with sickle cell disease].

Headache is a frequent symptom in sickle cell disease (SCD) that usually is attributable to anemia or cerebrovascular disease. We report 3 pediatric patients with SCD (1 patient with SCD-SC and 2 patients with SCD-SS) who presented with headache and were diagnosed with pseudotumor cerebri (PC). All 3 patients had elevated opening pressures during a lumbar puncture with normal cerebrospinal flui...

متن کامل

Cognitive Impairment in Patients with Pseudotumor Cerebri Syndrome

INTRODUCTION Patients with Pseudotumor Cerebri Syndrome (PTCS) may complain of difficulty in thinking or concentrating; however there has been little formal cognitive evaluation in this population. OBJECTIVE To evaluate the characteristics and nature of cognitive impairment in patients with PTCS. METHODS We retrospectively reviewed records of 10 patients diagnosed with PTCS who were cogniti...

متن کامل

The changing picture of pseudotumor cerebri in children.

Among 38 children with pseudotumor cerebri only 3 cases were due to ear disease or its complications. The commonest cause was a refeeding syndrome either due to nutritional deprivation or as an early finding in the treatment of cystic fibrosis. It is uncommon to find the cause of pseudotumor in older children but in those under 6 years the cause was found in 85%. Because of the adverse effects ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Frontiers in ophthalmology

سال: 2023

ISSN: ['2768-4121']

DOI: https://doi.org/10.3389/fopht.2022.1042529